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Photomicrograph of an AIDS-related lymphoma (a diffuse large cell lymphoma), which is one of the tumors used to make the tissue microarray (TMA) shown in the insert. TMA's of AIDS-related tumors are provided by the AIDS and Cancer Specimen Resource (ACSR) as a resource for research in this area.

Image courtesy of Dr. Leona Ayers, ACSR and Ohio State Comprehensive Cancer Center.

In addition to funding research on HIV/AIDS and HIV-malignancies, the NCI makes a number of resources available to investigators working in this area. Listed below is information on several useful resources provided by the NCI that are specific to research in HIV/AIDS and HIV-associated malignancies. Also listed are links to general resources provided by the NCI that may be of use to HIV/AIDS researchers, as well as selected resources provided by other components of the NIH.

NCI HIV/AIDS and AIDS Malignancy Resources
Selected Other NCI Resources
Other NIH Resources of Interest to HIV/AIDS Researchers

NCI HIV/AIDS and AIDS Malignancy Resources

AIDS and Cancer Specimen Resource (ACSR)
The ACSR, which is funded by OHAM, is a biorepository of HIV-infected human biospecimens, including tissues and biological fluids, obtained from a wide spectrum of HIV-related or associated diseases. Click here for more information about the ACSR and obtaining material for research purposes.

Information on compounds screened in the NCI in vitro anti-HIV screen
From 1987 through 1997, the Developmental Therapeutics Program (DTP) of the NCI maintained an anti-HIV screening program and screened many compounds, including many natural products. A repository of information on screening data and the chemical structures of the compounds screened are found on the DTP Website.

Reagents and Analytic Capabilities in the AIDS and Cancer Vaccine Program
Various reagents and analytical capabilities relevant to AIDS research are available through the AIDS and Cancer Virus Program at NCI Frederick. You can contact Tricia Grove (; 301 846 1408) for more information.

Selected Other NCI Resources

Directory of Resources Available from the NCI
A directory of a broad array of tools and research services for cancer researchers is found at the NCI Research Resources Website.

The NCI Biological Resources Branch (BRB) Repository
The BRB Preclinical Repository is an NCI-sponsored facility that contains bulk cytokines, monoclonal antibodies, cytokine standards, and other research reagents that are maintained under carefully controlled storage conditions. The purpose of this facility is to maintain and distribute a constant and uniform supply of high quality reagents for scientists at non-profit as well as commercial establishments.

Surveillance, Epidemiology and End Results (SEER) Program
SEER collects information on incidence, survival, and prevalence from specific geographic areas representing 26 percent of the US population. Information on these cancer statistics can be found on the SEER Website.

Other NIH Resources of Interest to HIV/AIDS Researchers

NIH AIDS Research and Reference Reagent Program
This program, created by the National Institute of Allergy and Infectious Diseases (NIAID), provides state-of-the-art biological and chemical materials for the study of HIV and related opportunistic pathogens to registered users worldwide at no cost. Click here for more information about this program.

National Center for Research Resources (NCRR)
NCRR, part of the NIH, provides laboratory scientists and clinical researchers with a variety of tools and training resources.

NIAID HIV Protein Interaction Database
The NIAID Protein Interaction Database provides a summary of known interactions of HIV proteins with host cell proteins, other HIV proteins, or proteins from disease organisms associated with HIV/AIDS.

Retrovirus Genome Database
National Center for Biotechnology Information (NCBI) has a database of retrovirus genomes and related resources, such as the HIV structural database, a listing of anti-HIV compounds, and the Stanford HIV drug resistance database. Click here to access these resources.